Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000064078

Apexbio Technology LLC Anhydrotetracycline (hydrochloride) 13803-65-1 250mg
SDP

Catalog No. 5000064078
Encompass_Preferred

Anhydrotetracycline hydrochloride (ATC) is an effector molecule utilized in tetracycline-controlled gene expression systems modulating the DNA-binding activity of tetracycline repressor protein (TetR) and its engineered variant reverse TetR (revTetR) TetR binds to operator DNA sequences inhibiting transcription ATC binding induces TetR conformational changes dissociating it from operator DNA enabling gene expression Conversely ATC acts as a corepressor in revTetR systems enhancing its DNA-binding inhibition ATC displays approximately 35-fold greater affinity towards TetR compared to tetracycline with an IC50 near 0 4 M employed in inducible gene expression studies in biological research contexts

Catalog No. 50-000-64078 Supplier Apexbio Technology LLC Supplier No. C4291250
May include imposed supplier surcharges.
Add to Cart
Add to Cart

Anhydrotetracycline hydrochloride (ATC) is an effector molecule utilized in tetracycline-controlled gene expression systems modulating the DNA-binding activity of tetracycline repressor protein (TetR) and its engineered variant reverse TetR (revTetR) TetR binds to operator DNA sequences inhibiting transcription ATC binding induces TetR conformational changes dissociating it from operator DNA enabling gene expression Conversely ATC acts as a corepressor in revTetR systems enhancing its DNA-binding inhibition ATC displays approximately 35-fold greater affinity towards TetR compared to tetracycline with an IC50 near 0 4 M employed in inducible gene expression studies in biological research contexts

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.