Apexbio Technology LLC Anisomycin 22862-76-6 50mg

Supplier:  Apexbio Technology LLC B667450

Anisomycin is an activator of c-Jun N-terminal kinase (JNK) a stress-activated protein kinase implicated in apoptotic signaling pathways regulating cell proliferation cell cycle progression and apoptosis It activates the JNK pathway at approximately 25 ng/ml concentration Experimental studies demonstrate anisomycin s capability to sensitize apoptosis-resistant cancer cell lines such as DU145 prostate carcinoma cells to Fas-mediated apoptosis as well as to induce apoptosis in leukemic HL-60 cells and primary mouse embryonic fibroblast cells by initiating JNK activation Anisomycin is thus widely utilized as a molecular tool in apoptosis-related research and insight into JNK-associated cell signaling

Catalog No. 50-000-63801