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Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 10 MG

Supplier: Medchemexpress LLC HYU0009610MG
Ansofaxine hydrochloride is a triple reuptake inhibitor that inhibits serotonin, dopamine, and norepinephrine reuptake. It is for research use only and not sold to patients. This compound rapidly penetrates the rat striatum, converts into desvenlafaxine, and shows greater total exposure compared to desvenlafaxine administration.
- Inhibits serotonin reuptake with IC50 value of 723 nM.
- Inhibits dopamine reuptake with IC50 value of 491 nM.
- Inhibits norepinephrine reuptake with IC50 value of 763 nM.
- Acute and chronic oral administration increases 5-HT, dopamine, and norepinephrine levels more than desvenlafaxine.
- Reduces immobility time more effectively than desvenlafaxine.
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