Medchemexpress LLC Ant308 (TFA) | 99.6% | 3467.10 | 5 MG

Supplier:  Medchemexpress LLC 5MGHYP11288A

ANT308 TFA is a vasoactive intestinal polypeptide (VIP receptor) antagonist. It significantly enhances the activation and proliferation of T cells, inhibits migration and metastasis, and induces apoptosis of melanoma tumor cells by inhibiting VIP-VPAC2 signaling and reducing the expression of MCAM and N-cadherin. It can be used for the study of acute myeloid leukemia (AML) and uveal melanoma (UVM).

• Reduces the viability of specific cell lines
• Decreases the proportion of cells in the S phase
• Induces apoptosis in certain cell types
• Inhibits cell migration in multiple cell lines
• Reduces MCAM and N-cadherin expression
• Reduces the number and size of liver metastases in animal models
• Shows a trend toward reducing tumor volume in primary tumor sites in animal models

Catalog No. 50-003-93407