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AdipoGen anti-8-Hydroxy-2'-deoxyguanosine [8-OHdG], mAb (N45.1)
SDP

Supplier:  AdipoGen JAIMOG100P

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anti-8-Hydroxy-2'-deoxyguanosine [8-OHdG], mAb (N45.1), AdipoGen Life Sciences. Monoclonal Antibody. Recognizes 8-OHdG. Does not cross-react with 19 analogues of 8-OHdG (guanosine (G), 7-methylG, 6-SHG, 8-bromoG, dA, dC, dT, dI, dU, dG, O6-methyldG, 8-OHdA, guanine (Gua), O6-methylGua, 8-OHGua, uric acid, urea, creatine, creatinine). Minimal cross-reactivity with 8-sulfhydrylG and 8-OHG (less than 1%). Lyophilized. Contains 10mM PBS, pH7.4 containing 1.0% BSA. 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals (incl. singlet oxygen and direct photodynamic action) that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress.

Catalog No. 50-101-5750


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