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ECM Bioscience GSK-3α/β (Tyr-279/Tyr-216), phospho-specific Mouse Monoclonal Antibody, ECM Biosciences
Supplier: ECM Bioscience GM1321
Clone M132 was generated from a phospho-GSK-3β (Tyr-216) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 216 of human GSK-3β. This peptide sequence is also found in GSK-3α (Tyr-279) and is highly conserved in GSK-3 genes in rat and mouse. Accession #P49841. This mouse monoclonal antibody was purified with protein A chromatography. The antibody detects 46/50 kDa* proteins corresponding to the apparent molecular mass of GSK-3β and GSK-3α on SDS-PAGE immunoblots of pervanadate treated rabbit fibroblasts, as well as treated human SKN-SH and A431 cells. Applications: WB, E; Species Reactivity: Hu, Rt, Ms; Size = 100 μl; Buffer = Mouse monoclonal purified with protein A chromatography is supplied in 100µl phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year. Other Names = Glycogen synthase kinasebeta3
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