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Bio X Cell Antibody, CD3, OKT-3, IgG2a Unconjugated, 5 MG
Supplier: Bio X Cell BE00012R005MG
The OKT-3 monoclonal antibody reacts with human CD3ε, a 20 kDa transmembrane cell-surface protein belonging to the immunoglobulin superfamily. It plays roles in TCR signaling, T lymphocyte activation, and antigen recognition. The OKT-3 antibody has immunosuppressive properties in vivo and has been shown to effectively treat renal, heart, and liver allograft rejection.
- Isotype: Mouse IgG2a, κ
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Purity: ≥95% by SDS-PAGE
- Endotoxin: ≤1 EU/mg
- Sterility: 0.2 μm filtered
- Production: Purified from cell culture supernatant in an animal-free facility
- Purification: Protein G
- Applications: In vitro T cell stimulation/activation, in vivo T cell depletion in humanized mice, ex vivo T cell inhibition for xenografts, Flow cytometry, in vitro Organoids/Organ-on-Chip
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