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Leinco Technologies Inc AAnti-Human CD11b (Mac-1, Integrin αM chain, C3biR, CR3, Mo1, ITGAM, SLEB6) In Vivo PLATINUM; Clone ICRF44 (44); Isotype: Mouse IgG1
Supplier: Leinco Technologies Inc C66825 MG
Specificity: Clone ICRF44 recognizes the subunit (CD11b) of the Human CD11b/CD18 complex. Antigen Distribution: CD11b is expressed on human peripheral blood lymphocytes, NK lymphocytes, monocytes, granulocytes, a subset of T-cells & macrophages. Background: The CD11b/CD18 antigen is a heterodimeric surface glycoprotein on leukocytes & belongs to the ß2 integrin family. CD11b (165-170 kDa) functions as a receptor for C3bi complement, clotting factor X, fibrinogen & ICAM-1. Applications: (FC, WB) Clone ICRF44 may be used to study lymphocyte subsets in flow cytometry & in cell adhesion research. It may be used to stain tissue sections which have been acetone fixed & frozen. Leinco’s In vivo GOLDTM & In vivo PLATINUMTM functional antibodies are manufactured in an animal free facility using only In vitro cell culture techniques & are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
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