Leinco Technologies Inc Anti-Human PD-L2 (B7-DC, CD273, PDL2, B7DC) In Vivo PLATINUM; Clone 3.2; Isotype: Mouse IgG1

Supplier:  Leinco Technologies Inc P6795.0 MG

Specificity: Clone 3.2 recognizes an epitope on mouse/human PD-L2. Antigen distribution: PD-L2 is expressed on dendritic cells, liver, few transformed cell lines, and a subset of macrophages. Background: PD-L2 is a 25 kD type I transmembrane ligand of PD-1, and a member of B7 Ig superfamily. Via PD-1,PD-L2 can serve as a coinhibitor of T cell functions. Regulation of T cell responses, including enhanced T cell proliferation and cytokine production, can result from mAbs that block the PD-L2 and PD-1 interaction. Applications: (WB, FA) Leinco’s In vivo GOLDTM and In vivo PLATINUMTM functional antibodies are manufactured in an animal free facility using only In vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Catalog No. 50-190-6616