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STEMCELL Technologies Anti-Human CD32 Antibody, Clone IV.3, FITC, Size: 25 Tests

Supplier: STEMCELL Technologies 60012FI.1

Clone IV.3 is a mouse monoclonal antibody that reacts with human CD32 (FcγRII), an ~40 kDa type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, immunomodulation, and platelet aggregation. Verified for use with enzyme-linked immunosorbent assay (ELISA), interferometry, and flow cytometry assays, use this antibody in applications requiring the detection of CD32. It is also verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Human T Cell Enrichment Kit (Catalog #19051) and EasySep™ Human CD4+ T Cell Enrichment Kit (Catalog #19052). CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes. These interactions can result in non-specific labeling in antibody-based detection and cell separation experiments and the IV.3 antibody may be employed as a blocking antibody to reduce non-specific binding. Visit STEMCELL.com for more information.
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