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STEMCELL Technologies Anti-Human CD326 (EpCAM) Antibody, Clone 323/A3, Size: 100 µg
Supplier: STEMCELL Technologies 60146
Clone 323/A3 is a mouse monoclonal antibody that reacts with the human epithelial cell adhesion molecule (CD326), an ~40 kDa type I transmembrane glycoprotein which functions as a homophilic and Ca++-independent adhesion molecule. Verified for use with flow cytometry and immunohistochemistry assays, use this antibody in applications requiring the detection of human CD326 (EpCAM). EpCAM has roles in several cellular processes, including signaling, migration, proliferation, and differentiation. It is expressed early during erythrogenesis and has been identified as a stem cell marker. The protein is found on the basolateral membrane of most normal epithelial cells and is highly expressed in bone marrow, colon, and lung. EpCAM is not expressed on mesothelial cells or mesotheliomas, and so is used as a diagnostic marker to distinguish mesothelioma and carcinoma cells, as well as serving as a target for immunotherapeutic treatment of carcinomas. Visit STEMCELL.com for more information.
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