Anti-IL-23a Antibody (Risankizumab) (CAS No 1612838-76-2) is a monoclonal antibody primarily used in immunology research It targets the p19 subunit of interleukin-23 (IL-23) a cytokine involved in inflammatory pathways pivotal to autoimmune conditions like psoriasis By inhibiting IL-23 Risankizumab modulates the signaling pathway that influences Th17 cell activation reducing inflammation Its in vitro activity is often observed in the nanomolar range Typical applications include the use of cell models such as keratinocytes and fibroblasts for inflammatory response assays as well as animal studies to evaluate its therapeutic potential in autoimmune disease models It is also utilized in drug screening to explore effectiveness against chronic inflammatory diseases Experimental concentrations typically depend on the specific research design ensuring precise targeting of the IL-23/Th17 axis for therapeutic exploration