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Enzo Life Sciences Polyubiquitin (K63-linkage-specific) monoclonal antibody (HWA4C4) (25 µl)

Supplier: Enzo Life Sciences BMLPW06000025

Key antibody for the detection of K.A monoclonal antibody (mAb) has been generated that specifically recognizes K63-linked polyubiquitin chains, but not any other isopeptide-linked (K.The hybridoma secreting the antibody [clone HWA4C4] was generated by fusion of splenocytes from Balb/c mice which had received repeated immunisation with a synthetic peptide encompassing the ubiquitin K63-isopeptide motif. Immunoglobulin was purified from tissue culture supernatant by ion exchange chromatography. Clone: HWA4C4. Host: Mouse. Isotype: IgG2a. Immunogen: Synthetic peptide containing the ubiquitin K63-isopeptide motif. Source: Purified from hybridoma tissue culture supernatant. Species Reactivity: Species independent. Specificity: Recognizes K63-linked polyubiquitin in wide range of species. Crossreactivity: Does not cross-react with any other isopeptide-linked (K6, K11, K27, K29, K33, or K48) polyubiquitinylated species. Applications: ELISA, ICC, IHC, WB.
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