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Bio X Cell Antibody, Anti-Mouse CTLA-4 (CD152), Clone 9H10, Unconjugated
Supplier: Bio X Cell BE0131R025MG
The 9H10 monoclonal antibody targets mouse CTLA-4 (CD152), a 33 kDa cell surface receptor on activated T and B lymphocytes. CTLA-4, similar to CD28, binds B7-1 and B7-2, negatively regulating immune responses. This antibody promotes T cell co-stimulation by blocking CTLA-4 binding to B7 co-receptors, allowing CD28 binding and supporting immunological tolerance and protective immunity.
- Purity of 95% or greater, determined by SDS-PAGE.
- Formulated in PBS, pH 7.0, without stabilizers or preservatives.
- Endotoxin levels at 1 EU/mg or less.
- Sterility ensured by 0.2 μm filtration.
- Produced in an animal-free facility with protein G purification.
- Suitable for in vivo and in vitro CTLA-4 neutralization.
- Can be used for western blot applications.
- Store at 4°C; do not freeze.
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