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Bio X Cell Anti-mouse ICOSL, HK5.3, Rat IgG2a, 5 MG
Supplier: Bio X Cell BE0028R005MG
The HK5.3 monoclonal antibody reacts with mouse ICOSL (inducible T cell co-stimulator ligand), also known as CD275, B7RP-1, and B7-H2. This 40 kDa immune checkpoint protein belongs to the Ig receptor superfamily. Upon ICOSL binding, ICOS signaling co-stimulates T and B cell responses, with the ligand expressed on antigen-presenting cells.
- Clone: HK5.3
- Target: ICOSL (CD275, B7RP-1, B7-H2)
- Species reactivity: Mouse
- Isotype: Rat IgG2a, κ
- Conjugation: Unconjugated
- Immunogen: Mouse B7-RP1 transfected cell line
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Endotoxin: ≤1 EU/mg (≤0.001 EU/μg)
- Purity: ≥95% by SDS-PAGE
- Sterility: 0.2 μm filtration
- Purification: Protein G
- Molecular weight: 150 kDa
- Storage: 4°C, do not freeze
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