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Bio X Cell Mouse CD28 Antibody 37.51, Unconjugated, 25 MG
Supplier: Bio X Cell BE00151R025MG
The 37.51 monoclonal antibody targets mouse CD28, a 45 kDa costimulatory receptor found on thymocytes, most peripheral T cells, and NK cells. It acts as a receptor for CD80 (B7-1) and CD86 (B7-2) and enhances IL-2 and IL-2 receptor expression, increases the cytotoxicity of CD3-activated T cells, and provides a costimulatory signal for CTL induction.
- Isotype: Syrian Hamster IgG2
- Immunogen: C57BL/6 mouse T cell lymphoma EL-4 cells
- Applications: in vitro T cell stimulation/activation, in vivo CD28 blockade
- Formulation: PBS, pH 6.0; 0.01% Tween; no stabilizers or preservatives
- Endotoxin: ≤1EU/mg
- Purity: ≥95%
- Sterility: 0.2 μm filtered
- Production: Purified from animal-free cell culture supernatant
- Purification: Protein G
- Molecular Weight: 150 kDa
- Storage: Store at stock concentration at 4°C. Do not freeze.
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