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Bio X Cell Antibody, Anti-Mouse CD4, Clone YTS 177, Rat IgG2a
Supplier: Bio X Cell BE00033R005MG
This monoclonal antibody reacts with mouse CD4, a 55 kDa cell surface glycoprotein crucial for T cell development and optimal function. Acting as a co-receptor with the T cell receptor, it interacts with MHC class II molecules. The antibody is non-depleting and induces rapid internalization of CD4, demonstrating potential in suppressing allograft rejection, allergic reactions, and autoimmune responses.
- Reacts with mouse CD4
- Isotype is rat IgG2a
- Suitable for in vivo blockade of CD4+ T-cell responses and western blot
- Immunogen: mouse spleen cells
- Formulated in PBS, pH 7.0, without stabilizers or preservatives
- Endotoxin level of ≤1EU/mg
- Purity of ≥95%
- 0.2 μm filtration for sterility
- Molecular weight of 150 kDa
- Store at 4°C; do not freeze
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