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Bio X Cell InVivoMAb, anti-mouse CD54, Rat IgG2b, 5 MG
Supplier: Bio X Cell BE00201R005MG
The YN1/1.7.4 monoclonal antibody reacts with mouse CD54, also known as Intercellular Adhesion Molecule-1 (ICAM-1). CD54 is a 90 kDa single-chain transmembrane glycoprotein that acts as a ligand for LFA-1 on leukocytes, facilitating transmigration into tissues. This antibody neutralizes CD54 in vivo, inhibiting CXCL1, IFNγ, and IL-17 production and neutrophil infiltration into inflammatory lesions.
- Reported applications: In vivo ICAM-1 neutralization, immunohistochemistry (frozen), ELISA
- Formulated in PBS, pH 7.0, containing no stabilizers or preservatives
- Purity: ≥95% determined by SDS-PAGE
- Endotoxin: ≤1EU/mg (≤0.001EU/µg), determined by LAL assay
- Sterility: 0.2 µm filtered
- Produced in an animal-free facility, purified by Protein G
- Store at 4°C; do not freeze
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