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Bio X Cell Antibody, Anti-Mouse CTLA-4, Clone 9D9, Mouse IgG2b
Supplier: Bio X Cell BE0164R025MG
This monoclonal antibody targets mouse CTLA-4 (CD152), a 33 kDa cell surface receptor expressed on activated T and B lymphocytes. It plays a critical role in negatively regulating cell-mediated immune responses and maintaining immunological tolerance. The antibody is widely used in blocking and neutralization experiments, with studies demonstrating its effectiveness in intra-tumoral regulatory T cell depletion.
- Reacts with mouse CTLA-4 (CD152)
- Clone 9D9
- Isotype: mouse IgG2b
- Unconjugated
- Formulation: PBS, pH 7.0, contains no stabilizers or preservatives
- Purity: ≥95%
- Sterility: 0.2 μm filtration
- Purified from cell culture supernatant in an animal-free facility
- Molecular weight: 150 kDa
- Reported applications: in vivo CTLA-4 neutralization, Western blot, in vivo intra-tumoral regulatory T cell depletion
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