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Bio X Cell Antibody, anti-mouse CTLA-4, Clone 9H10, 100 MG
Supplier: Bio X Cell BP0131R100MG
The 9H10 monoclonal antibody reacts with mouse CTLA-4 (CD152), a cell surface receptor that negatively regulates cell-mediated immune responses. This antibody promotes T cell co-stimulation by blocking CTLA-4 binding to B7 co-receptors, allowing for CD28 binding, which is critical in immune down-regulation and explored as a cancer treatment target.
- Monoclonal antibody (clone 9H10)
- Reacts with mouse CTLA-4 (CD152)
- Promotes T cell co-stimulation by blocking CTLA-4 binding
- InVivoMAb format for in vivo functional studies
- Purified from cell culture supernatant in an animal-free facility
- Sterility ensured by 0.2 μm filtration
- Low endotoxin level (≤1EU/mg)
- High purity (≥95%)
- Contains no stabilizers or preservatives
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