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Bio X Cell Monoclonal Antibody, anti-mouse IFNAR-1, Clone MAR1-5A3, Unconjugated
Supplier: Bio X Cell BE0241R005MG
The MAR1-5A3 monoclonal antibody targets mouse IFNAR-1 (IFN alpha/beta receptor subunit 1), forming a heterodimeric Type I IFN Receptor complex with IFNAR-2. This complex is vital for cellular responses to Type I IFNs, including anti-viral, anti-microbial, anti-tumor, and autoimmune responses. The antibody effectively inhibits Type I IFN receptor signaling both in vitro and in vivo.
- Clone: MAR1-5A3
- Host: Mouse
- Reactivity: Mouse IFNAR-1
- Isotype: Mouse IgG1, κ
- Purity: ≥95% by SDS-PAGE
- Unconjugated
- Immunogen: Extracellular domain of mouse IFNAR-1
- Applications: in vivo/in vitro IFNAR-1 blockade, Western blot, flow cytometry, ELISA
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Endotoxin: ≤1 EU/mg
- Sterility: 0.2 μm filtration
- Molecular weight: 150 kDa
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