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Bio X Cell Anti-mouse IL-10, Clone JES5-2A5, Rat IgG1, ≥95% Purity
Supplier: Bio X Cell BE0049R005MG
The JES5-2A5 monoclonal antibody specifically reacts with mouse IL-10, a cytokine involved in immunoregulation and inflammation. IL-10 plays pleiotropic roles including down-regulating Th1 cytokine expression, enhancing B cell activity, and regulating the JAK-STAT signaling pathway. This antibody has been shown to neutralize the bioactivity of natural or recombinant IL-10.
- Targets mouse IL-10
- Reactivity with mouse samples
- Rat IgG1, κ isotype
- Purity of ≥95% by SDS-PAGE
- Endotoxin level ≤1EU/mg
- Formulated in PBS, pH 7.0, without stabilizers or preservatives
- Molecular weight of 150 kDa
- Sterilized by 0.2 μm filtration
- Produced in an animal-free facility
- Protein G purification
- Store at 4°C; do not freeze
- Suitable for in vivo IL-10 neutralization
- Suitable for in vitro IL-10 neutralization
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