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Bio X Cell Antibody, Anti-Mouse/Rat IL-17A, Clone 17F3, Mouse IgG1, Unconjugated
Supplier: Bio X Cell BE0173R025MG
The 17F3 monoclonal antibody reacts with mouse IL-17A, a cytokine critical for immunoregulation and inflammation. It mediates anti-microbial responses, neutrophil influx, and antibacterial peptide production, while also acting as an inflammatory mediator in autoimmune diseases like rheumatoid arthritis, asthma, and psoriasis. This antibody has been shown to neutralize IL-17A in vivo.
- Clone 17F3
- Reactivity: mouse, rat
- Isotype: mouse IgG1, κ
- Recommended isotype control: mouse IgG1, unknown specificity
- Immunogen: mouse IL-17A cross-linked to OVA
- Applications: in vivo IL-17A neutralization, ELISA
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Endotoxin: ≤1 EU/mg
- Purity: ≥95%
- Sterility: 0.2 μm filtration
- Production: purified from animal-free cell culture supernatant
- Purification: protein G
- Molecular weight: 150 kDa
- Storage: 4°C, do not freeze
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