Bio X Cell Antibody, Anti-Mouse PD-1 (CD279), Clone J43, Unconjugated

Supplier:  Bio X Cell BE00332R005MG

The J43 monoclonal antibody reacts with mouse PD-1 (programmed death-1), also known as CD279. PD-1 is a 50-55 kDa cell surface receptor expressed on various immune cells. This antibody inhibits T-cell activation by blocking the binding of PD-L1 and PD-L2 to PD-1, playing key roles in peripheral tolerance and prevention of autoimmune disease. It is suitable for research in areas such as cancer immunotherapy and autoimmune disease studies.

• Reacts with mouse PD-1 (CD279).
• Used for in vivo blocking of PD-1/PD-L signaling.
• Suitable for in vitro PD-1 neutralization.
• Applicable for Western blot.
• Formulated in PBS, pH 6.5, without stabilizers or preservatives.
• Endotoxin level is ≤1 EU/mg.
• Purity is ≥95%.
• Sterilized by 0.2 µm filtration.
• Produced in an animal-free facility.
• Purified via Protein G.
• Store at stock concentration at 4°C.

Catalog No. 50-562-100