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Bio X Cell Antibody, Mouse PD-1, Clone RMP1-14, Rat IgG2a
Supplier: Bio X Cell BE0146R005MG
The RMP1-14 monoclonal antibody reacts with mouse PD-1 (programmed death-1), also known as CD279, a cell surface receptor crucial for immune regulation. This antibody effectively blocks the binding of both mouse PD-L1-Ig and mouse PD-L2-Ig to PD-1, inhibiting T-cell activation and thus playing key roles in peripheral tolerance and the prevention of autoimmune disease.
- Monoclonal antibody
- Rat IgG2a, κ isotype
- Immunogen: Syrian Hamster BKH cells with mouse PD-1 cDNA
- Purity: ≥95%
- Endotoxin: ≤1EU/mg
- Sterility: 0.2 μm filtration
- Purified from animal-free cell culture supernatant
- Protein G purification
- Store at 4°C, do not freeze
- Applications: In vivo PD-1/PD-L signaling blocking, in vitro Organoids/Organ-on-Chip
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