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Bio X Cell Antibody, anti-mouse PD-1, RMP1-14, IgG2a, 0.50 MG
Supplier: Bio X Cell BE0146R050MG
The RMP1-14 monoclonal antibody reacts with mouse PD-1 (CD279), a cell surface receptor crucial for immune regulation. It inhibits T-cell activation by blocking PD-L1 and PD-L2 binding, playing a key role in peripheral tolerance and cancer immunotherapy research.
- Reactivity: Mouse
- Clone: RMP1-14
- Isotype: Rat IgG2a, κ
- Applications: In vivo blocking of PD-1/PD-L signaling, in vitro organoids/organ-on-chip
- Purity: ≥95% (determined by SDS-PAGE)
- Sterility: 0.2 μm filtration
- Purification: Protein G
- Formulation: PBS, pH 7.0 (no stabilizers or preservatives)
- Endotoxin: ≤1EU/mg (≤0.001EU/μg)
- Molecular weight: 150 kDa
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