Bio X Cell Antibody, anti-mouse PD-1, Clone RMP1-14, Rat IgG2a

Supplier:  Bio X Cell BE0146R050MG

The RMP1-14 monoclonal antibody reacts with mouse PD-1 (programmed death-1, CD279), a cell surface receptor belonging to the CD28 family. Expressed on thymocytes, activated T and B lymphocytes, and myeloid cells, PD-1 signals by binding ligands PD-L1 and PD-L2. This binding inhibits T-cell activation, reducing proliferation, cytokine production, and T-cell death.

• Reacts with mouse PD-1 (CD279)
• Isotype: rat IgG2a, κ
• Applications: in vivo blocking of PD-1/PD-L signaling; in vitro organoids/organ-on-chip
• Formulation: PBS, pH 7.0, no stabilizers or preservatives
• Endotoxin: ≤1 EU/mg; purity: ≥95%
• Sterility: 0.2 μm filtered; protein G purification
• Molecular weight: 150 kDa
• Storage: 4°C, do not freeze

Catalog No. 50-562-457