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Bio X Cell InVivoMAb anti-mouse PD-1 Antibody, Clone RMP1-14, Rat IgG2a, Unconjugated
Supplier: Bio X Cell BE0146R100MG
The RMP1-14 monoclonal antibody targets mouse PD-1 (CD279), a key immune checkpoint receptor. It plays crucial roles in peripheral tolerance and preventing autoimmune diseases by inhibiting T-cell activation. This antibody effectively blocks the binding of both mouse PD-L1-Ig and mouse PD-L2-Ig to PD-1, making it valuable for research into immune modulation.
- Clone: RMP1-14
- Mouse reactivity
- Isotype: Rat IgG2a, κ
- Unconjugated
- Immunogen: Mouse PD-1 cDNA transfected Syrian Hamster BKH cells
- Formulation: PBS, pH 7.0 (no stabilizers/preservatives)
- Endotoxin: ≤1EU/mg
- Purity: ≥95% (SDS-PAGE)
- Sterile (0.2 μm filtration)
- Animal-free production
- Purification: Protein G
- Molecular weight: 150 kDa
- Storage: 4°C (do not freeze)
- Application: In vivo PD-1/PD-L signaling blocking
- Application: In vitro organoids/organ-on-chip
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