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Bio X Cell Monoclonal Antibody, mouse PD-L1 (B7-H1), 10F.9G2, Rat IgG2b
Supplier: Bio X Cell BE0101R005MG
This monoclonal antibody targets mouse PD-L1 (B7-H1/CD274), a 40 kDa type I transmembrane protein expressed on various immune and endothelial cells. The antibody blocks the interaction between PD-L1 and its receptors, PD-1 and B7-1 (CD80), thereby regulating T cell activation and potentially impacting tumor immune evasion.
- Targets mouse PD-L1 (B7-H1)
- Isotype: Rat IgG2b, κ
- Molecular weight: 150 kDa; Purity: ≥95%
- Sterile 0.2 μm filtration
- Formulated in PBS, pH 6.5, without stabilizers or preservatives
- Purified from animal-free cell culture supernatant via protein G
- Reported applications: PD-L1 blockade (in vivo/in vitro), immunofluorescence, IHC (frozen), flow cytometry, western blot, in vitro organoids/organ-on-chip
- Store at stock concentration at 4°C; Do not freeze
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