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STEMCELL Technologies Anti-Mouse CD49b Antibody, Clone DX5, APC, Size: 100 µg
Supplier: STEMCELL Technologies 60020AZ
Clone DX5 is a rat monoclonal antibody that reacts with mouse CD49b (integrin α2), an ~150 kDa type 1 transmembrane glycoprotein that associates non-covalently with CD29 (integrin β1) to form the heterodimeric CD49b/CD29 complex known as VLA-2, a receptor for extracellular matrix proteins such as collagen, E-cadherin, fibronectin, and laminin. Verified for use with flow cytometry assays, use this antibody in applications requiring the detection of CD49b (Integrin α2). The DX5 antibody is particularly useful for identifying NK cells in mice lacking the NK1.1 antigen. Binding of the DX5 antibody has not been observed to affect the function of the VLA-2 integrin. DX5 binding is, however, blocked by the clone HMα2 antibody. This antibody clone has been verified for purity assessments of cells isolated with EasySep™ Mouse NK Cell Enrichment Kit (Catalog #19755). Visit STEMCELL.com for more information and related products.
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