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STEMCELL Technologies Anti-Mouse CD49f Antibody, Clone GoH3, Pacific Blue™, Size: 25 Tests
Supplier: STEMCELL Technologies 60037PB.1
Clone GoH3 is a rat monoclonal antibody that reacts with human, mouse, and rhesus CD49f (integrin α6), an ~150 kDa transmembrane glycoprotein that associates non-covalently with CD29 (integrin β1) or CD104 (integrin β4) to form the heterodimeric receptors VLA-6 and α6β4, which bind the extracellular matrix protein laminin. Verified for use with flow cytometry assays, use this antibody in applications requiring the detection of CD49f (Integrin α6). CD49f is considered the most important marker for selecting mouse mammary stem and progenitor cells. The GoH3 antibody reacts with an extracellular epitope on CD49f and reportedly blocks integrin α6 function in vivo and binding of integrin α6 to laminin in vitro. Visit STEMCELL.com for more information and related products.
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