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Bio X Cell RecombiMAb Anti-Mouse GITR DTA-1-CP029 Clone, 1 MG
Supplier: Bio X Cell CP029R001MG
The recombinant DTA-1-CP029 monoclonal antibody is a chimeric version of the original DTA-1, engineered with LALA-PG mutations to prevent binding to murine Fcγ receptors. This modification reduces anaphylaxis in mice while preserving T cell agonistic and antitumor efficacy. It targets mouse GITR, a co-stimulatory immune checkpoint molecule on T lymphocytes and regulatory T cells.
- Clone: DTA-1-CP029
- Host: Mouse
- Target: Mouse GITR
- Isotype: Mouse IgG2a LALA-PG, κ
- Purity: ≥95% by SDS-PAGE
- Endotoxin: ≤0.5EU/mg
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Storage: 4°C; do not freeze
- Applications: Flow cytometry, Western Blot, Immunoprecipitation, in vitro/in vivo T cell stimulation, in vivo antitumor immunity
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