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Leinco Technologies Inc Anti-Mouse CD86 (B7-2, B70, Ly-58) In Vivo PLATINUM; Clone GL-1; Isotype: Rat IgG2a κ
Supplier: Leinco Technologies Inc C6158100 MG
Specificity: Clone GL-1 recognizes an epitope on mouse CD86. Antigen Distribution: This antigen is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. Background: CD86 is an 80 kDa glycoprotein and a member of the Ig superfamily. CD86 is a ligand for CD28 and CD152 (CTLA-4). CD86 is related to the CD80 molecule and functions as a counter receptor for CD28 and CTLA-4. The GL1 clone has been shown to provide critical signals for T-Cell-dependent responses In vivo and In vitro. Applications: (WB, B, IF) Clone GL1 has been shown to block CD86 In vivo and inhibit the priming of cytotoxic T cells. Leinco’s In vivo GOLDTM and In vivo PLATINUMTM functional antibodies are manufactured in an animal free facility using only In vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
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