Leinco Technologies Inc Anti-Mouse PD-L1 (Programmed Death Ligand 1, B7-H1, PD-L1, CD274) In Vivo PLATINUM; Clone 10F.9G2; Isotype: Rat IgG2b κ

Supplier:  Leinco Technologies Inc P37125 MG

Specificity: Clone 10F.9G2 recognizes an epitope on mouse PD-L1. Antigen Distribution: PD-L1 is present on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. Background:PD-L1 is a 40 kD type I transmembrane protein and is part of the B7 Ig superfamily. The interaction of PD-1 with its ligand PD-L1 is critical in the inhibition of T cell responses that include T cell proliferation and cytokine production. PD-L1 has been reported to costimulate T cell growth and cytokine production. Applications: (WB, B, FA) Clone 10F.9G2 has been shown to block the interaction between PD-L1 and PD-1 and between PD-L1 and B7-1. Leinco’s In vivo GOLDTM and In vivo PLATINUMTM functional antibodies are manufactured in an animal free facility using only In vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Catalog No. 50-190-6572