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Leinco Technologies Inc Anti-Mouse ICAM-1 (BB2, CD54, P3.58) In Vivo GOLD; Clone BE29G1; Isotype: Rat IgG2a
Supplier: Leinco Technologies Inc C3911.0 MG
Specificity: Clone BE29G1 recognizes mouse ICAM-1. Antigen Distribution: CD54 is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. Background: CD54 is a 55 kDa transmembrane glycoprotein that is part of the Ig superfamily. It is heavily glycosylated to form 75 kDa to 115 kDa. CD54 is the receptor for rhinoviruses and malaria. It is critical for the arrest and transmigration of leukocytes out of blood vessels and into tissues, and is a marker of endothelial dysfunction leading to damaging vascular disorders in umbilical and placental vascular tissue of gestational pregnancies. Applications: (IHC (NBF/Par.), FC, IP, WB) Leinco’s In vivo GOLDTM and In vivo PLATINUMTM functional antibodies are manufactured in an animal free facility using only In vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
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