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Leinco Technologies Inc Anti-Mouse CD8a (Ly 2, T8, Lyt 2, Ly-2) In Vivo GOLD; Clone 53-6.7; Isotype: Rat IgG2a κ
Supplier: Leinco Technologies Inc C37525 MG
Specificity: Clone 53-6.7 recognizes Lyt 2. Antigen Distribution: Present on the surface of most thymocytes and a subpopulation of mature T-lymphocytes which include most T suppressor/cytotoxic cells. Background: CD8a is a 34 kD protein that is part of the immunoglobulin family. CD8a is part of the larger CD8 complex consisting of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8 participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck. Applications: (IP, WB) The antibody precipitates 44 kDa and 33 kDa proteins and reacts with non-polymorphic determinant. Leinco’s In vivo GOLDTM and In vivo PLATINUMTM functional antibodies are manufactured in an animal free facility using only In vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
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