Cayman Chemical ANTI-OVALBUMIN IGG EIA KIT 96W

Supplier:  Cayman Chemical 50083096WELLS

Immunization of mice with chicken egg albumin (ovalbumin/OVA) in a precipitate complex with aluminum hydroxide (alum) is a highly effective means of inducing a potent TH2-mediated immune response.{20137,20136,20138,20141,20140,20139} OVA/alum immunized mice produce anti-OVA antibodies predominantly of the IgG1 and IgE isotypes that mediate tissue-specific effector functions in multiple mouse models of chronic inflammation, including allergic asthma, allergic rhinitis, and cutaneous hypersensitivity.{20137,20136,20138,20141},When using one of these models, it is often desirable to measure anti-OVA antibody levels in the plasma or serum to determine the effectiveness of the immunization, the activity of a drug, or the effect of a specific gene deletion. IgG1 is the predominant anti-OVA immunoglobulin isotype found in the serum or plasma of mice immunized with OVA/alum; the plasma concentration of OVA-specific IgG1 is typically 1,000-fold greater than that of OVA-specific IgE.{20137} Ther

Catalog No. NC0720743