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KRISHGEN BIOSYSTEMS Immunoassay for the quantitative Determination of Anti-Pembrolizumab antibodies in human serum and plasma. Assay Range: 10 - 640 ng/ml; Sensitivity: 8.75 ng/ml.
Supplier: KRISHGEN BIOSYSTEMS KBI2084
Pack Size: 1 x 96 wells. This Anti-Pembrolizumab ELISA accurately quantifies antibodies to pembrolizumab in human samples. If you are looking to use animal samples, please contact us. ELISA Features include a pre-coated plate with break-apart wells, standardisation and Lot to Lot Consistency with Precision CV <15%.Background: Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, stomach cancer, and cervical cancer. Pembrolizumab was approved for medical use in the United States in 2014. ADA has been observed in pre-clinical and clinical studies, resulting in significant changes in toxicology, pharmacokinetics and efficacy. These effects result from the generation of drug-induced (neutralizing) autoantibodies against Pembrolizumab and can be responsible for allergic reaction, or even anaphylactic shock.
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