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STEMCELL Technologies Anti-Phospho-SHIP Antibody, Polyclonal, Size: 100 µL
Supplier: STEMCELL Technologies 60142
This rabbit polyclonal antibody reacts with human and mouse SH2-containing inositol phosphatase (SHIP), a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. Verified for use with flow cytometry and western blotting assays, use this antibody in applications requiring the detection of tyrosine-phosphorylated SHIP. SHIP hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. Visit STEMCELL.com for more information and related products.
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