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AdipoGen anti-Polyglutamate chain [Poly-E], pAb (IN105)

Supplier: AdipoGen AG25B0030C050

anti-Polyglutamate chain [Poly-E], pAb (IN105), AdipoGen Life Sciences. Polyclonal Antibody. Recognizes C-terminally located linear glutamate chains of 4 and more glutamate residues. Source: Rabbit. Applications: ICC, WB. Liquid. In PBS containing 0.02% sodium azide. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and beta-tubulin genes, referred to as tubulin isotypes, and the generation of posttranslational modifications (PTMs) on alpha- and beta-tubulin. Tubulin PTMs include the well-known acetylation or phosphorylation, and others that have so far mostly been found on tubulin, detyrosination/tyrosination, polyglutamylation and polyglycylation. These PTMs might have evolved to specifically regulate tubulin and microtubule functions.
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