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Cayman Chemical ANTIBODY 9 S-HpOTrE 500ug

Supplier: Cayman Chemical 45120500 UG

An inhibitor of JAK1 JAK2 JAK3 and TYK2 (IC50s 2.8 2.6 13 and 58 nM respectively) is selective for JAK1 JAK2 JAK3 and TYK2 over LCK (IC50 5800 nM) inhibits IL-31-induced increases in STAT3 phosphorylation levels in A549 cells (IC50 25 nM) reduces IL-31-induced scratching in mice in a dose-dependent manner
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