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Cayman Chemical ANTIBODY A-485 10mg
Supplier: Cayman Chemical 2411910 MG
A p300/CBP inhibitor (IC50 = 60 nM); decreases H3K27Ac levels in PC3 cells; reduces proliferation of various tumor cell lines; inhibits expression of PSA and H3K27Ac occupancy at the PSA enhancer in LNCaP-FGC cells; reduces tumor volume in a LuCaP-77 mouse xenograft model of castration-resistant prostate cancer at 100 mg twice per day for 21 days
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