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Cayman Chemical ANTIBODY A-771726 25mg
Supplier: Cayman Chemical 1440425 MG
An active metabolite of leflunomide; inhibits DHODH (IC50 = 0.23 µM); inhibits the production of PGE2 in TNF-α- or IL-1α-stimulated isolated human synoviocytes (IC50s = 7 and 3 μM, respectively); inhibits the proliferation of isolated human PBMCs at 25 and 100 µM; delays disease onset and decreases neurological deficits in a rat model of EAE induced by CFA and M. tuberculosis at 3 and 10 mg/kg
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