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Cayman Chemical AF-DX 116, Purity: ≥98%, CAS: 102394-31-0, 1 mg
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Catalog No. 502989901
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A muscarinic M2 receptor antagonist (Ki = 0.2 µM); selective for cardiac M2 over salivary gland M3 receptors (Ki = 5.01 µM) but also binds sympathetic ganglia M1 receptors (Ki = 0.81 µM); increases vagus nerve stimulation-induced increases in perfusion pressure by 50% in isolated perfused rat hearts at 0.1 µM; increases systolic blood pressure and heart rate in a rat model of hypotension induced by repeated cold stress at 50, 100, and 200 µg/kg

Catalog No. 50-298-9901 Supplier Cayman Chemical Supplier No. 308711 MG
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A muscarinic M2 receptor antagonist (Ki = 0.2 µM); selective for cardiac M2 over salivary gland M3 receptors (Ki = 5.01 µM) but also binds sympathetic ganglia M1 receptors (Ki = 0.81 µM); increases vagus nerve stimulation-induced increases in perfusion pressure by 50% in isolated perfused rat hearts at 0.1 µM; increases systolic blood pressure and heart rate in a rat model of hypotension induced by repeated cold stress at 50, 100, and 200 µg/kg

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