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Cayman Chemical ANTIBODY AFN-1252 25mg
Supplier: Cayman Chemical 2468625 MG
An inhibitor of staphylococcal FabI (Ki = 12.8 nM); selective for isolates of methicillin-susceptible and methicillin-resistant S. aureus (MIC90s = ≤0.008 μg/ml) over isolates of S. pneumoniae, β-hemolytic streptococci, Enterococcus, Enterobacteriaceae, non-fermentative Gram-negative bacilli, and M. catarrhalis (MIC90s = >4 μg/ml); increases survival in a murine acute lethal septicemia model at 1 mg/kg
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