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Cayman Chemical AMG 837, Purity: ≥98%, CAS: 865231-46-5, 1 mg
SDP

Catalog No. 502985966
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An FFAR1 (GPR40) partial agonist; induces calcium mobilization in CHO cells expressing FFAR1/GPR40 but not FFAR2/GPR43, FFAR3/GPR41, or FFAR4/GPR120 (EC50s = 0.0135, >10, >10, and >10 µM, respectively); induces insulin secretion in MIN6 pancreatic β-cells and isolated mouse islets (EC50s = 0.0048 and 0.142 µM, respectively); decreases plasma glucose levels and increases plasma levels of insulin in Zucker fa/fa rats at 0.3, 1, and 3 mg/kg; decreases plasma glucose and increases plasma insulin levels in a mouse model of diabetes induced by a high-fat diet and streptozotocin

Catalog No. 50-298-5966 Supplier Cayman Chemical Supplier No. 218151 MG
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An FFAR1 (GPR40) partial agonist; induces calcium mobilization in CHO cells expressing FFAR1/GPR40 but not FFAR2/GPR43, FFAR3/GPR41, or FFAR4/GPR120 (EC50s = 0.0135, >10, >10, and >10 µM, respectively); induces insulin secretion in MIN6 pancreatic β-cells and isolated mouse islets (EC50s = 0.0048 and 0.142 µM, respectively); decreases plasma glucose levels and increases plasma levels of insulin in Zucker fa/fa rats at 0.3, 1, and 3 mg/kg; decreases plasma glucose and increases plasma insulin levels in a mouse model of diabetes induced by a high-fat diet and streptozotocin

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