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Cayman Chemical ANTIBODY AUTEN-99 10mg
Supplier: Cayman Chemical 3004710 MG
An inhibitor of MRMR14/Jumpy; inhibits MTMR14/Jumpy activity in a cell-free assay at 10 and 100 µM; enhances autophagic flux and increases the levels of LC3B-11 in HeLa cells at 1 and 10 µM; increases survival of mouse primary neurons exposed to hydrogen peroxide as a model of oxidative stress at 0.5-5 µM; increases the number of autophagic structures in mouse pancreas, kidney, and liver; induces autophagy in the Drosophila larval fat body and increases the percentage of flies climbing a glass column in a climbing assay in a transgenic model of Parkinson’s disease
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