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Cayman Chemical AZ82, Purity: ≥98%, CAS: 1449578-65-7, 5 mg
SDP

Catalog No. 502987159
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An inhibitor of KIFC1; binds to the KIFC1/microtubule complex and inhibits its microtubule-stimulated activity (IC50 = 300 nM) in an ATP-competitive (Ki = 43 nM) and microtubule-noncompetitive manner; does not inhibit basal KIFC1 activity at a concentration of 100 µM; selective for KIFC1 over a panel of nine kinesin motor proteins at a concentration of 5 µM; AZ82 preferentially induces multipolar spindle formation in cancer cell lines with high numbers of extra chromosomes

Catalog No. 50-298-7159 Supplier Cayman Chemical Supplier No. 218985 MG
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An inhibitor of KIFC1; binds to the KIFC1/microtubule complex and inhibits its microtubule-stimulated activity (IC50 = 300 nM) in an ATP-competitive (Ki = 43 nM) and microtubule-noncompetitive manner; does not inhibit basal KIFC1 activity at a concentration of 100 µM; selective for KIFC1 over a panel of nine kinesin motor proteins at a concentration of 5 µM; AZ82 preferentially induces multipolar spindle formation in cancer cell lines with high numbers of extra chromosomes

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