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Cayman Chemical BAY-3827, Purity: ≥98%, CAS: 2377576-35-5, 5 mg
SDP

Catalog No. 502944315
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An AMPK inhibitor (IC50 = 1.4 nM at 10 µM ATP); selective for AMPK over Aurora A kinase, FLT3, and c-Met (IC50s = 1,324, 124, and 788 nM, respectively), RSK2, RSK3, RSK4, MSK1, and MST3 (IC50s = 52, 36, 24, 43, and 94 nM, respectively), and a panel of 331 kinases at 10 µM but does inhibit RSK1 (IC50 = 9 nM); selectively inhibits the proliferation of androgen-dependent LNCaP, VCaP, and 22Rv1 prostate cancer cells (IC50s = 0.28, 1.71, and 5.55 µM, respectively) over androgen receptor-negative C4-2B, PC3, and DU145 prostate cancer cells (IC50s = >10 µM for all)

Catalog No. 50-294-4315 Supplier Cayman Chemical Supplier No. 414485 MG
May include imposed supplier surcharges.
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An AMPK inhibitor (IC50 = 1.4 nM at 10 µM ATP); selective for AMPK over Aurora A kinase, FLT3, and c-Met (IC50s = 1,324, 124, and 788 nM, respectively), RSK2, RSK3, RSK4, MSK1, and MST3 (IC50s = 52, 36, 24, 43, and 94 nM, respectively), and a panel of 331 kinases at 10 µM but does inhibit RSK1 (IC50 = 9 nM); selectively inhibits the proliferation of androgen-dependent LNCaP, VCaP, and 22Rv1 prostate cancer cells (IC50s = 0.28, 1.71, and 5.55 µM, respectively) over androgen receptor-negative C4-2B, PC3, and DU145 prostate cancer cells (IC50s = >10 µM for all)

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