Cayman Chemical ANTIBODY BAY-474 25mg

Supplier:  Cayman Chemical 4145125 MG

An antibacterial peptide active against a panel of eight Gram-negative bacteria including E. coli P. aeruginosa and S. syphimurium (MIC50s 4-8 UM) and the Gram-positive bacteria S. aureus MRSA-3126 B. subtilis and S. epidermidis (MIC50s 4-8 UM) without affecting the viability of human erythrocytes RAW 264.7 macrophages HaCaT keratinocytes or HEK293 kidney cells at 25 UM induces membrane depolarization in E. coli at 4 and 8 UM preincubation reduces NO2- Tnf-a and Il-6 secretion levels in LPS-stimulated RAW 264.7 macrophages at 10 UM increases survival in E. coli-infected mice infected at 10 mg/kg reduces the number of CFUs in the lungs liver and kidneys in E. coli-infected mice at 1 mg/kg reduces serum AST and ALT levels and blood urea nitrogen levels in a mouse model of E. coli-induced sepsis at 1 mg/kg

Catalog No. 50-294-3585