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Cayman Chemical BI-9627, Purity: ≥95% (mixture of tautomers), CAS: 1204329-34-9, 5 mg
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Catalog No. 502937860
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An NHE1 inhibitor (IC50s = 6 and 31 nM in pHi and human platelet swelling assays, respectively); greater than 30-fold selective for NHE1 over NHE2 and is inactive at NHE3 up to 16 μM in a pHi assay; inhibits phenylephrine-induced hypertrophy in neonatal rat cardiomyocytes; increases recovery of left ventricular developed pressure and inhibits increases in LVEDP in a Langendorff isolated perfused rat heart model of ischemia-reperfusion injury at 100 nM; attenuates decreases in left ventricular end-systolic pressure and increases in LVEDP in coronary artery-ligated rats at 45 and 150 ppm in the diet

Catalog No. 50-293-7860 Supplier Cayman Chemical Supplier No. 276405 MG
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An NHE1 inhibitor (IC50s = 6 and 31 nM in pHi and human platelet swelling assays, respectively); greater than 30-fold selective for NHE1 over NHE2 and is inactive at NHE3 up to 16 μM in a pHi assay; inhibits phenylephrine-induced hypertrophy in neonatal rat cardiomyocytes; increases recovery of left ventricular developed pressure and inhibits increases in LVEDP in a Langendorff isolated perfused rat heart model of ischemia-reperfusion injury at 100 nM; attenuates decreases in left ventricular end-systolic pressure and increases in LVEDP in coronary artery-ligated rats at 45 and 150 ppm in the diet

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